When Amy Carmichael felt God was calling her to missionary service, she wrote to her mother on 14 January 1892:
“My precious Mother, have you given your child unreservedly to the Lord for whatever He wills?”
(Frank Houghton, “Amy Carmichael of Dohnavur”)
"Therefore the Lord himself will give you a sign: The virgin will be with child and will give birth to a son, and you will call him Immanuel."
Isaiah 7: 14